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Key Takeaways
- Atelocollagen is pure collagen that has had the Telopeptide (the part that causes allergic reactions) removed. This makes it highly pure and very compatible with human skin.
- It works in two ways: Immediate Filling (fills deep grooves right away) and Bio-Scaffold (stimulates your body to produce new natural collagen).
- Collagen in your body decreases with age — after 25, you lose about 1–1.5% per year.
- It’s great for under-eye hollows, fine lines, large pores, and dull skin — helping you look smoother and brighter.
- Three main types of collagen matter for beauty: Type I (skin structure), Type II (cartilage & joints), and Type III (youthful skin & blood vessels).
- Atelocollagen vs. Rh Collagen: Atelocollagen comes from natural sources and focuses on adding volume. Rh Collagen is made with biotechnology and focuses more on stimulation.
- You’ll see some results immediately, with the best results typically appearing within 7–14 days.
- Results last about 6–12 months. You can have repeat treatments to keep your skin’s collagen structure strong over time.
What Is Pure Collagen (Atelocollagen)?
Atelocollagen is collagen that has gone through an advanced biological extraction process to remove the ends of the molecule, called Telopeptide.
What is Telopeptide?
It’s the part of the collagen molecule that can cause allergic reactions (antigens) in humans.
What happens when it’s removed?
You get collagen that is extremely pure — with a structure nearly 100% identical to the collagen in your own skin. This means your body doesn’t see it as a foreign substance, reducing the risk of allergies and inflammation to nearly zero.
How Does TheraFill Work?
TheraFill : When Atelocollagen is injected into the dermis (the middle layer of your skin), it works in two ways at the same time:
- Immediate Filling – It instantly replaces lost or shrunken collagen, helping to lift wrinkles and soften deep grooves.
- Bio-Scaffold – It acts like a “scaffold” that attracts your skin’s natural collagen-producing cells (fibroblasts). These cells then produce fresh, new collagen around it — making your skin firmer from the inside out.
What Causes Collagen Loss in Your Skin?
- Factor → How It Affects Collagen
- Aging → After age 25, collagen decreases by 1–1.5% per year
- Sun exposure → UV rays directly damage collagen structure
- Lifestyle → Smoking, high sugar intake (glycation), and lack of sleep
- Pollution → PM2.5 dust and free radicals speed up skin aging
What Can Pure Collagen (Atelocollagen) Help With?
- Under-eye area – Reduces dark circles and fills hollow tear troughs for a brighter, fresher look
- Fine lines – Treats forehead creases or crow’s feet that Botox might not fully smooth out
- Pores – Makes skin smoother and pores appear smaller
- Brightness – Collagen helps reflect light, giving you a radiant, non-dull complexion
Types of Collagen (Important for Beauty)
The human body has over 28 types of collagen. These are the 3 most important for beauty:
- Type Where It’s Found What It Does
- Type I 90% of your skin Strength and elasticity (Atelocollagen is this type)
- Type II Cartilage & joints Cushioning and joint health
- Type III Youthful skin & blood vessels Works with Type I to keep skin soft and bouncy
Atelocollagen vs. Rh Collagen – What’s the Difference?
Atelocollagen Atelocollagen is extracted from natural sources — usually from animals raised in controlled, closed systems. It’s then carefully purified. Its main strength is high stability. Atelocollagen is better at adding volume and tends to last longer, making it a great choice for filling deep grooves and restoring thickness to the skin.
Rh Collagen (Recombinant Human Collagen) Rh Collagen is made using genetic engineering — often with yeast or plants — to create a structure that closely mimics human collagen. It’s extremely pure, but its main focus is more on stimulation rather than adding volume. It’s best suited for gentle collagen stimulation, especially for those who want a very natural, gradual improvement.
Frequently Asked Questions (FAQ)
It’s real, natural collagen that has been purified to the highest level — not a synthetic plastic-based substance.
Yes, very natural. Atelocollagen has a whitish, cloudy color similar to real tissue — unlike clear gel fillers, it won’t cause a bluish tint or Tyndall effect under the skin.
Yes. Because it replaces the exact type of collagen your skin has lost. When your skin is full of healthy collagen, wrinkles fade and your skin becomes more elastic — just like younger skin.
About 6–12 months, depending on your original skin condition and lifestyle habits.
Yes. For best results, we recommend 2–3 initial sessions (about 1 month apart) to build a strong collagen foundation.
Yes, it’s excellent for thin skin. Atelocollagen helps increase skin thickness, making it stronger and less prone to irritation.
You’ll see about 70–80% improvement immediately after the injection. The best, most noticeable results appear within 7–14 days — once the product has fully blended with your tissue and any minor needle swelling has disappeared.
Summary
Atelocollagen is an excellent choice for anyone who wants natural, delicate results — especially around the eyes and for fine lines. If you’re tired of dark under-eye circles or worried that filler might make your face look “off” or unnatural, pure collagen (Atelocollagen) offers a safe, sustainable, and long-term solution for beautiful, healthy skin.
Read this article in Thai: คอลลาเจนบริสุทธิ์ (Atelocollagen) คืออะไร? ทำไมคนถึงนิยมฉีด?
Thank you to our reference source: Skin Changes with Aging (NIA)
